ICAR Research Data Repository for Knowledge Management
Interaction of Co, Mn, Mg and Al with d(GCGTACGC): a spectroscopic study.
IR@CSIR-CFTRI
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http://ir.cftri.com/2261/
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| Title |
Interaction of Co, Mn, Mg and Al with d(GCGTACGC): a spectroscopic study.
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| Creator |
Rajan, M. T.
Kumar, D. C. Vishnuvardhan, D. Rao, K. S. Viswamitra, M. A. |
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| Subject |
03 Biochemistry & Molecular Biology
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| Description |
Spectroscopic study on the interactions of trace elements Co., Mn, Mg and Al with d(GCGTACGC) indicated the following: Al and Mg did not alter Tm values. Mn enhanced Tm at lower concentration and decreased it at higher concentrations. Interestingly Co at higher concentration elevated the Tm. These studies also showed lower concentrations of Mn displaced EtBr, whereas Al could displace it at higher ionic strength. Mg and Co displaced EtBr fluorescence at moderate concentrations. The binding constant values and CD spectra clearly indicated strong binding of these elements to DNA.
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| Date |
1998
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Language |
en
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| Rights |
—
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| Identifier |
http://ir.cftri.com/2261/1/Cellular%20and%20Molecular%20Life%20Sciences%201998%2054%285%29%20488.pdf
Rajan, M. T. and Kumar, D. C. and Vishnuvardhan, D. and Rao, K. S. and Viswamitra, M. A. (1998) Interaction of Co, Mn, Mg and Al with d(GCGTACGC): a spectroscopic study. Molecular Biology Reports, 22 (1). pp. 47-52. ISSN 0301-4851 |
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