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Gibberellic acid by solid state fermentation: Consistent and improved yields.

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Relation http://ir.cftri.com/2380/
 
Title Gibberellic acid by solid state fermentation: Consistent and improved yields.
 
Creator Kumar, P. K.
Lonsane, B. K.
 
Subject 04 Fermentation Technology
 
Description Five strains each of Gibberella fujikuroi and Fusarium monoliforme were screened to select G. fujikuroi P-3, a strain capable of giving consistent production of gibberellic acid (GA(3)) by solid state fermentation (SSF). The comparative production of GA(3) by SSF and submerged fermentation (SmF) indicated better productivity with the former technique. The accumulation of GA(3) was 1.626 times higher in the case of SSF. On the basis of available carbohydrates in the media, the percent conversions were 0.096 and 0.156 in SmF and SSF, respectively. The use of coarse wheat bran of the particle size of 0.3-0.4 cm resulted in an increase of 2.5 times in the yield of GA(3). The enrichment of commercial wheat bran with soluble starch gave enhanced accumulation to an extent of 3.5 times. The relation between GA(3) production and cell growth in SSF was similar to that encountered in SmF. The consistent and improved yields to a tune of 1.22 g GA(3) per kilogram dry moldy bran (DMB) establish the potential and feasibility of SSF for the production of GA(3) by G. fujikuroi P-3. On preliminary cost analysis, a net savings of about 60% and 50% on fermentation medium cost and the expenditure on down-stream processing, respectively, as compared to the presently employed SmF technique was evident.
 
Date 1987
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/2380/1/Biotechnology%20and%20Bioengineering%2C%20Vol.%20XXX%2C%20Pp.%20267-271%20%281987%29.pdf
Kumar, P. K. and Lonsane, B. K. (1987) Gibberellic acid by solid state fermentation: Consistent and improved yields. Biotechnology and Bioengineering, 30 (2). pp. 267-71. ISSN 0006-3592