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Histidine metabolism in experimental protein malnutrition in rats.

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Relation http://ir.cftri.com/2387/
 
Title Histidine metabolism in experimental protein malnutrition in rats.
 
Creator Rao, D. R.
Deodhar, A. D.
Hariharan, K.
 
Subject 11 Malnutrition
05 Enzymes
 
Description 1. The activities of the enzymes histidase, urocanase and histidine-pyruvate transaminase were studied in rats under conditions of protein malnutrition. Urocanase and histidase activities in liver were markedly lowered in experimental protein malnutrition, but the activity of histidine-pyruvate transaminase was unaffected. There is a metabolic control in vivo of the enzymes involved in the catabolism of histidine. 2. Significant changes in the urinary excretion of histidine, composition of liver and serum were apparent in the protein-malnourished rat. 3. The changes in the activities of the enzymes and other parameters were of a reversible nature and dependent on the nature of the dietary protein. 4. The significance of these findings is discussed in relation to abnormal histidine metabolism in kwashiorkor.
 
Date 1965
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/2387/1/Biochemical_Journal_1965_97_1_311-317.pdf
Rao, D. R. and Deodhar, A. D. and Hariharan, K. (1965) Histidine metabolism in experimental protein malnutrition in rats. The Biochemical journal, 97 (1). pp. 311-7. ISSN 0264-6021