Interaction of amino acids, N-acetylamino acid esters, thymine and adenine with sephadex LH-20 GEL.
IR@CSIR-CFTRI
View Archive InfoField | Value | |
Relation |
http://ir.cftri.com/4492/
JOC-02-75 |
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Title |
Interaction of amino acids, N-acetylamino acid esters, thymine and adenine with sephadex LH-20 GEL.
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Creator |
Prakash, V.
Nandi, P. K. |
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Subject |
03 Amino Acid Chemistry
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Description |
N-Acctyl aromatic amino acid esters, tryptophan, adenine and thymine show strong retention in Sephadex LH-20 gel in an aqueous phase. The decreased retention in 6 M urea. the absence of retention in absolute methanol and the increased retention at higher temperatures in the aqueous phase indicate that hydrophobic interaction is responsible for the observed retention of the amino acids and their esters in the gel. Adenine was found to be retained by polar interaction in the gel. The increased retention of the solutes in the presence of different electrolytes suggests that the lyotropic effect is more important than the ionic strength effect. The relevance of the results obtained with amino acids and esters to the conformational aspects of proteins in aqueous solution is discussed. |
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Date |
1975
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Language |
en
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Rights |
—
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Identifier |
http://ir.cftri.com/4492/1/Journal_of_Chromatography_A%2C_Volume_106%2C_Issue_1%2C_19_March_1975%2C_Pages_23-33.pdf
Prakash, V. and Nandi, P. K. (1975) Interaction of amino acids, N-acetylamino acid esters, thymine and adenine with sephadex LH-20 GEL. Journal of Chromatography, 106 (1). pp. 23-31. |
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