Enzyme Catalyzed Synthesis of Serotonyl and Epinephryl Glycosides Using Amyloglucosidase from Rhizopus Mold.
IR@CSIR-CFTRI
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Relation |
http://ir.cftri.com/11706/
http://www.cibtech.org/jls.htm |
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Title |
Enzyme Catalyzed Synthesis of Serotonyl and Epinephryl Glycosides Using Amyloglucosidase from Rhizopus Mold.
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Creator |
Ganesan, V.
Divakar, S. |
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Subject |
16 Enzyme Chemistry
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Description |
Glycosylation of phenolic hydroxyl groups of serotonin and epinephrine, using an amyloglucosidase from Rhizopus mold was carried out with D-glucose, D-galactose, D-mannose and D-ribose in di-isopropyl ether solvent to yield 13-29% of glycosides in 48h. NMR spectroscopic data indicated that the reaction occurred between the phenolic -OH group of serotonin and C1α /β and / or 6-O-groups of D-glucose, D-galactose, D-mannose and D-ribose. In case of epinephrine, 4 –OH and 3 –OH groups reacted with C1 β anomer of D-glucose and C-1 α/β anomers of D-mannose.
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Date |
2011
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Language |
en
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Rights |
—
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Identifier |
http://ir.cftri.com/11706/1/Ind%20Jl%20of%20Fundamental%20and%20Applied%20Life%20Sci_2011_1%282%29.pdf
Ganesan, V. and Divakar, S. (2011) Enzyme Catalyzed Synthesis of Serotonyl and Epinephryl Glycosides Using Amyloglucosidase from Rhizopus Mold. Indian Journal of Fundamental and Applied Life Sciences, 1 (2). pp. 15-21. ISSN 2231-6345 |
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