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Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review.

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Relation http://ir.cftri.com/11825/
http://dx.doi.org/10.3390/md12010128
 
Title Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review.
 
Creator Ranga Rao, A.
Siew Moi, Phang
Sarada, R.
Ravishankar, G. A.
 
Subject 14 Carotenoid Chemistry
Fish
 
Description There is currently much interest in biological active compounds derived from natural resources, especially compounds that can efficiently act on molecular targets, which are involved in various diseases. Astaxanthin (3,3′-dihydroxy-β, β′-carotene-4,4′-dione) is a xanthophyll carotenoid, contained in Haematococcus pluvialis, Chlorella zofingiensis, Chlorococcum, and Phaffia rhodozyma. It accumulates up to 3.8% on the dry weight basis in H. pluvialis. Our recent published data on astaxanthin extraction, analysis, stability studies, and its biological activities results were added to this review paper. Based on our results and current literature, astaxanthin showed potential biological activity in in vitro and in vivo models. These studies emphasize the influence of astaxanthin and its beneficial effects on the metabolism in animals and humans. Bioavailability of astaxanthin in animals was enhanced after feeding Haematococcus biomass as a source of astaxanthin. Astaxanthin, used as a nutritional supplement, antioxidant and anticancer agent, prevents diabetes, cardiovascular diseases, and neurodegenerative disorders, and also stimulates immunization. Astaxanthin products are used for commercial applications in the dosage forms as tablets, capsules, syrups, oils, soft gels, creams, biomass and granulated powders. Astaxanthin patent applications are available in food, feed and nutraceutical applications.
The current review provides up-to-date information on astaxanthin sources, extraction, analysis, stability, biological activities, health benefits and special attention paid to its commercial applications.
 
Date 2014
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Rights —
 
Identifier http://ir.cftri.com/11825/1/Mar.%20Drugs%202014%2C%2012%281%29%2C%20128-152.pdf
Ranga Rao, A. and Siew Moi, Phang and Sarada, R. and Ravishankar, G. A. (2014) Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review. Marine Drugs, 12. pp. 128-152.