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Biochemical Characterization of Fat Soluble Nutraceuticals Loaded Liposome.

IR@CSIR-CFTRI

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Relation http://ir.cftri.com/11850/
 
Title Biochemical Characterization of Fat Soluble Nutraceuticals Loaded Liposome.
 
Creator Diksha, Sharma
 
Subject 11 Lipid Biochemistry
 
Description Tocopherol and oryzanol are fat soluble bioactives, known to have health beneficial effect, whose stability need to be retained for proper functioning. With this regard, liposome, a biocompatible vehicle can be used for safe delivery of the bioactives. Current work was focused on egg lecithin in combination with cholesterol as liposome for the encapsulation of tocopherols and oryzanol and studied the morphology as well as characterization of prepared liposome using phase contrast microscopy, particle size analyzer, FT-IR, HPLC and UV spectrophotometer. The obtained results confirmed that, the encapsulated particles were spherical and entrapped bioactives. Liposome was treated with specific gastrointestinal enzymes for the lecithin to release the entrapped bioactives with dose dependent manner. Particles when exposed to diverse pH, there was no release of bioactives, indicating its stability.
 
Contributor Suresh Kumar, G.
 
Date 2014
 
Type Student Project Report
NonPeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/11850/1/Diksha.pdf
Diksha, Sharma (2014) Biochemical Characterization of Fat Soluble Nutraceuticals Loaded Liposome. [Student Project Report] (Submitted)