ICAR Research Data Repository for Knowledge Management
Microwave assisted bi-functional activation of β-bromo-tert-alcohols.
IR@CSIR-CFTRI
View Archive Info| Field | Value | |
| Relation |
http://ir.cftri.com/12030/
http://dx.doi.org/10.1007/s12039-015-0906-y |
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| Title |
Microwave assisted bi-functional activation of β-bromo-tert-alcohols.
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| Creator |
Nandini, Kannan
Manjunatha, J. R. Bettadaiah, B. K. |
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| Subject |
24 Organic Chemistry
30 Spices/Condiments |
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| Description |
Microwave-assisted dehydration-oxidation of β-bromo-tert-alcohols to afford 2,3-unsaturated ketones in good yield is reported. The reaction of substrates with DMSO in 1:1 ratio (w/v) is promoted by ZnS in a solvent-free condition. A concurrent bi-functional activation of trans-vicinal bromo- and hydroxyl groups with ZnS is elucidated. This is a new observation under microwave and applies to β-bromo-tert-alcohols derived from 1,4-disubstitued-1-cyclohexenes. It is very useful in the synthesis of 2,3-unsaturated ketones derived from monoterpenes which are valuable flavour compounds. |
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| Date |
2015
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Language |
en
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| Rights |
—
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| Identifier |
http://ir.cftri.com/12030/1/Journal%20of%20Chemical%20Sciences%20August%202015%2C%20Volume%20127%2C%20Issue%208%2C%20pp%201405-1410.pdf
Nandini, Kannan and Manjunatha, J. R. and Bettadaiah, B. K. (2015) Microwave assisted bi-functional activation of β-bromo-tert-alcohols. Journal of Chemical Sciences, 127 (8). pp. 1405-1410. |
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