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Immunomodulatory activity of purified arabinoxylans from finger millet (Eleusine coracana, v. Indaf 15) bran.

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Relation http://ir.cftri.com/12041/
http://dx.doi.org/10.1007/s13197-014-1664-4
 
Title Immunomodulatory activity of purified arabinoxylans
from finger millet (Eleusine coracana, v. Indaf 15) bran.
 
Creator Savitha Prashanth, M. R.
Shruthi, R. R.
Muralikrishna, G.
 
Subject 28 Polysaccharide Chemistry
05 Ragi (Finger Millet)
 
Description Biological activities of alkali extracted (Barium
hydroxide: BE-480 kDa, Potassium hydroxide: KE1-1080
and KE2-40 kDa), purified arabinoxylans (AX) from the
finger millet bran varying in their molecular weight, phenolic
acid content, arabinose to xylose ratios were evaluated for
their immune-stimulatory activities using murine lymphocytes
and peritoneal exudate macrophages. All three purified
AX displayed significant (p2 fold) and macrophage phagocytosis than KE1 and
KE2. The above results clearly documented that the
immunostimulatory activity of arabinoxylans is directly proportional
to the amount of ferulic acid content (0.11 mg/
100 g), whereas molecular weight as well as arabinose/
xylose ratio, did not have any bearing. Purified AX from the
finger millet bran can be explored as a potent natural
immunomodulator.
 
Date 2015
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/12041/1/Journal%20of%20Food%20Science%20and%20Technology%20September%202015%2C%20Volume%2052%2C%20Issue%209%2C%20pp%206049-6054.pdf
Savitha Prashanth, M. R. and Shruthi, R. R. and Muralikrishna, G. (2015) Immunomodulatory activity of purified arabinoxylans from finger millet (Eleusine coracana, v. Indaf 15) bran. Journal of Food Science and Technology, 52 (9). pp. 6049-6054. ISSN 0022-1155