Immunomodulatory activity of purified arabinoxylans from finger millet (Eleusine coracana, v. Indaf 15) bran.
IR@CSIR-CFTRI
View Archive InfoField | Value | |
Relation |
http://ir.cftri.com/12041/
http://dx.doi.org/10.1007/s13197-014-1664-4 |
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Title |
Immunomodulatory activity of purified arabinoxylans from finger millet (Eleusine coracana, v. Indaf 15) bran. |
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Creator |
Savitha Prashanth, M. R.
Shruthi, R. R. Muralikrishna, G. |
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Subject |
28 Polysaccharide Chemistry
05 Ragi (Finger Millet) |
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Description |
Biological activities of alkali extracted (Barium hydroxide: BE-480 kDa, Potassium hydroxide: KE1-1080 and KE2-40 kDa), purified arabinoxylans (AX) from the finger millet bran varying in their molecular weight, phenolic acid content, arabinose to xylose ratios were evaluated for their immune-stimulatory activities using murine lymphocytes and peritoneal exudate macrophages. All three purified AX displayed significant (p2 fold) and macrophage phagocytosis than KE1 and KE2. The above results clearly documented that the immunostimulatory activity of arabinoxylans is directly proportional to the amount of ferulic acid content (0.11 mg/ 100 g), whereas molecular weight as well as arabinose/ xylose ratio, did not have any bearing. Purified AX from the finger millet bran can be explored as a potent natural immunomodulator. |
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Date |
2015
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Language |
en
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Rights |
—
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Identifier |
http://ir.cftri.com/12041/1/Journal%20of%20Food%20Science%20and%20Technology%20September%202015%2C%20Volume%2052%2C%20Issue%209%2C%20pp%206049-6054.pdf
Savitha Prashanth, M. R. and Shruthi, R. R. and Muralikrishna, G. (2015) Immunomodulatory activity of purified arabinoxylans from finger millet (Eleusine coracana, v. Indaf 15) bran. Journal of Food Science and Technology, 52 (9). pp. 6049-6054. ISSN 0022-1155 |
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