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Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation

IR@CSIR-CFTRI

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Relation http://ir.cftri.com/12147/
 
Title Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation
 
Creator Chidananda, C.
Vasantha, K. Y.
Sattur, A. P.
 
Subject 04 Fungi
 
Description Sclerotiorin, isolated from the fermented broth of Penicillium frequentans, exhibited potent inhibition against human polymorphonuclear leukocytes 5-lipoxygenase and human platelet aggregation with a half maximal value 36 µM and 250 µM, respectively. Further, the Ames test has demonstrated the sclerotiorin to be non-mutagenic.
 
Date 2015
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/12147/1/IJEB%2053%284%29%20228-231.pdf
Chidananda, C. and Vasantha, K. Y. and Sattur, A. P. (2015) Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation. Indian Journal of Experimental Biology, 53 (4). pp. 228-231.