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Health and Wellness Product from Mangosteen (Garcinia mangostana L.) Rind: Bioactive Potentials

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Relation http://ir.cftri.com/12377/
 
Title Health and Wellness Product from Mangosteen (Garcinia
mangostana L.) Rind: Bioactive Potentials
 
Creator Shashirekha, M. N.
Shylaja, M. Dharmesh
Shivaleela, V. Bhimangouder
Mallikarjuna, S. E.
Rajarathnam, S.
 
Subject 04 Functional foods
24 Fruits
 
Description Mangosteen rind (MSR) (Garcinia mangostana L.) is a predominant component of the fruit contributing to 62%
of the whole fruit. However, utilization of the same for the preparation of health products was not explored due to its
sensorially less acceptable parameters. Differential extraction in different polarity solvents of MSR was done and
evaluated their acceptability for product preparation. Current study thus is a detailed investigation on bioactivity profiling
of MSR fraction and utilization of the same for health product preparation. Among various extracts, 70% ethanol
(70%AE) yielded the maximum (15g/100g). Xanthone:Phenolic ratio was 1: 2.8, in 70%AE as opposed to hot water
extract – HWE and 50% AE, which contained Xanthone:Phenolic ratio of 1:1.4/5. Higher the phenolic content obviously
reduces the bitterness of Xanthones. 70% AE contained phenolics 60.08± 0.213 mg/g and xanthones 22.56± 0.317
mg/g. HPLC analysis revealed a spectrum of phenolic acids such as gallic, chlorogenic, caffeic, epicatechin, catechin
and ferulic acids at various levels. Potent Free Radical Scavenging (FRS) activity, cytoprotectivity, DNA protectivity,
H+K+ATPase inhibitory (PPAI) activities were observed in 70% AE. Gallic/tannic acid appear to contribute to antioxidant
activity; while ferulic acid was responsible for PPAI activity in 70%AE. Among xanthones, although
 
Date 2014
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
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Identifier http://ir.cftri.com/12377/1/International%20Journal%20of%20Biotechnology%20for%20Wellness%20Industries%2C%202014%2C%203%2C%20111-120.pdf
Shashirekha, M. N. and Shylaja, M. Dharmesh and Shivaleela, V. Bhimangouder and Mallikarjuna, S. E. and Rajarathnam, S. (2014) Health and Wellness Product from Mangosteen (Garcinia mangostana L.) Rind: Bioactive Potentials. International Journal of Biotechnology for Wellness Industries, 3. pp. 111-120.