Sulphated galactopyran derived from Gracilaria opuntia, a marine macroalgae restores the antioxidant metabolic enzymes during STZ induced diabetic rats
CMFRI Repository
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Relation |
http://eprints.cmfri.org.in/11538/
http://oaji.net/articles/2017/2154-1485309660.pdf |
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Title |
Sulphated galactopyran derived from Gracilaria opuntia, a marine macroalgae restores the antioxidant metabolic enzymes during STZ induced diabetic rats |
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Creator |
Lavanya, R
Makkar, Fasina Anusree, M Chakraborty, Kajal Valluru, Lokanatha |
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Subject |
Bioactive compounds
Algae |
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Description |
In vitro antioxidant assays of FM4 were estimated by DPPH, ABTS, hydroxyl free radical and Nitric oxide free radical activities. FM4 was purified and characterized by 1H-NMR spectra and FTIR as sulphated galactopyran. Diabetes was induced intraperitonially by single dose of STZ (55 mg/kg body weight). FM4 was administrated orally (80, 100, 125 mg/kg BW) to diabetic rats for 60 days. The enzymatic and non-enzymatic antioxidants such as superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), glutathione-S-transferase (GST), lipid peroxidase (LPx), glutathione reduced (GSH), vitamin-C (VIT-C) and vitamin-E (VIT-E) levels were estimated. Glibenclamide was used as standard drug. |
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Date |
2017
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Type |
Article
PeerReviewed |
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Format |
text
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Language |
en
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Identifier |
http://eprints.cmfri.org.in/11538/1/Journal%20of%20Coastal%20Life%20Medicine_galactopyran%20from%20Gracilaria_2017_Kajal%20Chakraborty.pdf
Lavanya, R and Makkar, Fasina and Anusree, M and Chakraborty, Kajal and Valluru, Lokanatha (2017) Sulphated galactopyran derived from Gracilaria opuntia, a marine macroalgae restores the antioxidant metabolic enzymes during STZ induced diabetic rats. Journal of Coastal Life Medicine, 5 (2). pp. 59-65. |
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