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A new antitumor isoquinoline alkaloid from the marine nudibranch Jorunna funebris

DRS at CSIR-National Institute of Oceanography

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Title A new antitumor isoquinoline alkaloid from the marine nudibranch Jorunna funebris
 
Creator Fontana, A.
Cavaliere, P.
Wahidullah, S.
Naik, C.G.
Cimino, G.
 
Subject marine molluscs
chemical extraction
skin
mucus
metabolites
spectroscopic techniques
nuclear magnetic resonance
alkaloides
Jorunna funebris
 
Description A new dimeric isoquinoline alkaloid, jorumycin (3), has been isolated from the skin and the mucus of the Pacific nudibranch Jorunna funebris. The structure has been fully elucidated on the grounds of ESMS data and of an extensive 2D NMR analysis. The cytotoxicity of 3 was evaluated against various human cancer cell lines and was found to be slightly less potent than Et 743 (2)
 
Date 2009-01-09T07:54:11Z
2009-01-09T07:54:11Z
2000
 
Type Journal Article
 
Identifier Tetrahedron, Vol.56; 7305-7308p.
http://drs.nio.org/drs/handle/2264/1638
 
Language en
 
Rights Copyright [2000]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
 
Publisher Pergamon