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Total synthesis of (-)- and (+)-tedanalactam

DRS at CSIR-National Institute of Oceanography

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Field Value
 
Title Total synthesis of (-)- and (+)-tedanalactam
 
Creator Majik, M.S.
Parameswaran, P.S.
Tilve, S.G.
 
Subject tedanalactam
enantiomers
piperidone
oxidation-Wittig reaction
 
Description The first stereoselective route providing access to both enantiomers of tedanalactam, a naturally occurring piperidone, has been developed. The stereogenic centers were generated by the use of Sharpless asymmetric dihydroxylation. Tandem oxidation-Wittig reaction and one-pot deprotection, lactamization, and oxirane ring formation are the other key elements
 
Date 2009-12-18T09:04:24Z
2009-12-18T09:04:24Z
2009
 
Type Journal Article
 
Identifier The Journal of Organic Chemistry, vol.74(16); 6378-6381
http://drs.nio.org/drs/handle/2264/3477
 
Language en
 
Rights Copyright ACS [2009]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
 
Publisher American Chemical Society