Total synthesis of (-)- and (+)-tedanalactam
DRS at CSIR-National Institute of Oceanography
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Title |
Total synthesis of (-)- and (+)-tedanalactam
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Creator |
Majik, M.S.
Parameswaran, P.S. Tilve, S.G. |
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Subject |
tedanalactam
enantiomers piperidone oxidation-Wittig reaction |
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Description |
The first stereoselective route providing access to both enantiomers of tedanalactam, a naturally occurring piperidone, has been developed. The stereogenic centers were generated by the use of Sharpless asymmetric dihydroxylation. Tandem oxidation-Wittig reaction and one-pot deprotection, lactamization, and oxirane ring formation are the other key elements
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Date |
2009-12-18T09:04:24Z
2009-12-18T09:04:24Z 2009 |
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Type |
Journal Article
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Identifier |
The Journal of Organic Chemistry, vol.74(16); 6378-6381
http://drs.nio.org/drs/handle/2264/3477 |
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Language |
en
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Rights |
Copyright ACS [2009]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
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Publisher |
American Chemical Society
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