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Marine metabolites: The sterols of soft coral

DRS at CSIR-National Institute of Oceanography

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Title Marine metabolites: The sterols of soft coral
 
Creator Sarma, N.S.
Krishna, M.S.
Pasha, Sk.G.
Rao, T.S.P.
Venkateswarlu, Y.
Parameswaran, P.S.
 
Subject marine invertebrates
chemical extraction
metabolites
coral
 
Description Sterols constitute a major group of secondary metabolites of soft corals. Several of these compounds have the 'usual' 3 beta-hydroxy, delta sup(5) (or delta sup(0)) cholestane skeleton, a large number of these metabolites are polar sterols with multiple oxygenations in rings as well as side chains. The latter compounds are structurally similar to some of the steroidal hormones, bile acids, signaling agents, etc., with potential therapeutic applications in the fields of cancer, atherosclerosis, and other diseases. The present review lists 561 structurally diverse sterols of marine soft coral origin and attempts to codify their structural types. This will help in chemotaxonomic investigations of these organisms and stimulate biochemists to look for useful enzymes for conversion of normal sterols into biologically useful derivatives.
 
Date 2009-12-21T06:45:22Z
2009-12-21T06:45:22Z
2009
 
Type Journal Article
 
Identifier Chemical Reviews, vol.109(6); 2803-2828
http://drs.nio.org/drs/handle/2264/3490
 
Language en
 
Rights © 2009 American Chemical Society. All efforts have been made to respect the copyright to the best of our
knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
 
Publisher American Chemical Society