ICAR Research Data Repository for Knowledge Management
Tandem Wittig-ene reaction approach to kainic acid
DRS at CSIR-National Institute of Oceanography
View Archive Info| Field | Value | |
| Title |
Tandem Wittig-ene reaction approach to kainic acid
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| Creator |
Majik, M.S.
Parameswaran, P.S. Tilve, S.G. |
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| Subject |
bioactive compounds
amino acids kainic acid Tandem Wittig-ene reaction |
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| Description |
The first example of a tandem Wittig-intramolecular ene reaction approach and its application toward the synthesis of kainic acid is reported. The synthetic pathway involves conversion of prenyl bromide into phosphorane 3, followed by one-pot Wittig olefination and an ene reaction with glyoxalic acid to give the cis fused pyrrolidine skeleton of kainic acid.
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| Date |
2009-12-21T11:52:05Z
2009-12-21T11:52:05Z 2009 |
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| Type |
Journal Article
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| Identifier |
The Journal of Organic Chemistry, vol.74(9); 3591-3594
http://drs.nio.org/drs/handle/2264/3498 |
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| Language |
en
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| Rights |
© 2009 American Chemical Society. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository. |
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| Publisher |
American Chemical Society
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