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Calamenenes - aromatic bicyclic sesquiterpenes - from the Indian gorgonian Subergorgia reticulata (Ellis and Solander, 1786)

DRS at CSIR-National Institute of Oceanography

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Title Calamenenes - aromatic bicyclic sesquiterpenes - from the Indian gorgonian Subergorgia reticulata (Ellis and Solander, 1786)
 
Creator LimnaMol, V.P.
Raveendran, T.V.
Naik, B.G.
Kunnath, R.J.
Parameswaran, P.S.
 
Subject Calamenenes
bioactivity
Subergorgia reticulata
Balanus amphitrite
Artemia nauplii
 
Description Three aromatic sesquiterpene derivatives, (+)-(7R, 10S)-2-methoxy calamenene (1), (+)-(7R, 10S)-2,5-dimethoxy calamenene (2) and (+)-(7R, 10S)-2-methoxy-5-acetoxy calamenene (3) were isolated from the methanol extract of the Indian gorgonian Subergorgia reticulata. Compound 2 has not been previously described in the literature. Compound 3 has not been isolated previously from a natural source. Compounds 1, 2 and 3 showed settlement inhibition activity against cyprids of Balanus amphitrite with EC sub (50) values of 4.4, 7.8 and 0.03 mu g mL sup(-1), respectively. These compounds also exhibited considerable activity against Artemia nauplii at 50 mu g mL sup(-1), indicative of their potential use as cytotoxic agents
 
Date 2011-01-25T06:16:30Z
2011-01-25T06:16:30Z
2011
 
Type Journal Article
 
Identifier Natural Product Research, vol.25(2); 2011; 169-174
no
http://drs.nio.org/drs/handle/2264/3781
 
Language en
 
Relation Nat_Prod_Res_25_169.jpg
 
Rights The final and definitive form of the preprint has been published in the "Natural Product Research" ? 2011 Taylor & Francis; "Natural Product Research" is available online at http://www.informaworld.com/ with open URL of artilce : http://www.informaworld.com/smpp/content~db=all?content=10.1080/14786419.2010.495069
 
Publisher Taylor & Francis