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(-)-6 alpha hydroxy polyanthellian A - A novel antifouling diterpenoid from the Indian soft coral Cladiella krempfi (Hickson)

DRS at CSIR-National Institute of Oceanography

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Title (-)-6 alpha hydroxy polyanthellian A - A novel antifouling diterpenoid from the Indian soft coral Cladiella krempfi (Hickson)
 
Creator LimnaMol, V.P.
Raveendran, T.V.
Parameswaran, P.S.
Kunnath, R.J.
Rajamohanan, P.R.
 
Subject biofouling
antifouling
Cladiella krempfi
Balanus amphitrite
 
Description Bioassay-guided purification of methanol extract of the soft coral Cladiella krempfi (Octocorallia: Alcynocea) yielded a novel eunicellin-type diterpenoid, (-)-6 alpha-hydroxy polyanthellin A (1), active against the cyprids of the fouling barnacle, Balanus amphitrite (EC sub(50) 9.02 mu g/mL; LC sub(50) 36 mg/mL; and therapeutic ratio = 4). The structure of compound 1 was determined from its spectral data, including IR, NMR (1D and 2D NMR), and mass spectra
 
Date 2011-03-11T09:35:41Z
2011-03-11T09:35:41Z
2011
 
Type Journal Article
 
Identifier Canadian Journal of Chemistry, vol.89(1); 2011; 57-60
http://drs.nio.org/drs/handle/2264/3819
 
Language en
 
Rights An edited version of this paper was published by NRC Research Press. This paper is for R & D purpose and Copyright [2011]
 
Publisher NRC Research Press