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Bio-screening of a few green seaweeds from India for their cytotoxic and antioxidant potential

DRS at CSIR-National Institute of Oceanography

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Title Bio-screening of a few green seaweeds from India for their cytotoxic and antioxidant potential
 
Creator Vinayak, R.C.
Sabu, A.S.
Chatterji, A.
 
Subject seaweeds
toxicity tolerance
disease resistance
Caulerpa racemosa
Caulerpa peltata
Caulerpa taxifolia
Chlorodesmis fastigiata
Codium elongatum
 
Description Seaweeds, raw, cooked, or dried, are used as food in many cultures, although not very popularly in India. Globally, several studies have indicated that seaweeds are a rich source of phenolic compounds and have antioxidant properties. Methanolic extracts (MEs) of five species of green seaweeds commonly found in India were screened for their cytotoxic activity by brine shrimp lethality assay and antioxidant properties using various in vitro assays, including 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reducing power and metal ion chelating assays. A markedly variable, dose-dependent activity was observed in all the seaweed extracts relative to their total phenolic content. Statistical analysis indicated a significantly strong correlation between the DPPH radical scavenging activity and total phenolic content (R sup(2) = 0.88, P < 0.05) as well as reducing power and total phenolic content (R sup(2) = 0.99, P < 0.01) of the dry MEs. Also, a very poor correlation between total phenolic content and metal chelating activity (R sup(2) = 0.13, P > 0.05) was noted. None of the seaweed extracts were potently cytotoxic. The underlying results endorse seaweeds as a rich, novel source of antioxidant compounds needing systemic exploration.
 
Date 2011-11-09T12:10:06Z
2011-11-09T12:10:06Z
2011
 
Type Journal Article
 
Identifier Journal of the Science of Food and Agriculture, vol.91; 2011; 2471?2476
http://drs.nio.org/drs/handle/2264/3944
 
Language en
 
Rights ? 2011 Society of Chemical Industry. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
 
Publisher Society of Chemical Industry