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Protective role of edible clam Paphia malabarica (Chemnitz) against lipid peroxidation and free radicals

DRS at CSIR-National Institute of Oceanography

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Title Protective role of edible clam Paphia malabarica (Chemnitz) against lipid peroxidation and free radicals
 
Creator Pawar, R.T.
Nagvenkar, S.S.
Jagtap, T.G.
 
Subject antioxidants
seafood
nutritive value
lipids
 
Description In vitro inhibition of lipid peroxidation and free radical scavenging properties of a seafood Paphia malabarica (Chemnitz) as a natural source of antioxidants was observed. Antioxidant activities of Paphia malabarica extracts were tested spectrophotometrically against 2,2-diphenyl-2-picryl-hydrazyl, hydroxyl radical scavenging, in vitro inhibitions of lipid peroxidation and results were presented as percentage relative activities by comparing with standard synthetic antioxidant compounds. In addition, reducing potentials and presence of antioxidant compound in sample extract was tested with exponential increase in absorbance and ferric reducing antioxidant power values respectively. The scavenging potential of 2,2-diphenyl-2-picryl-hydrazyl radical and reducing action increased in a dose dependent manner. Inhibition of lipid peroxidation shown by methanol extract and its significant correlation with OH scavenging activity implies its potential to protect the cell damage against reactive oxygen species. Increasing antioxidant equivalents of ascorbic acid in ferric reducing antioxidant power assay further supported its role in reducing reactions. Dose dependant antioxidant responses by methanolic extracts of clam P. malabarica and their role in breaking chain reactions of lipid peroxidation highlights its potentials against reactive oxygen species mediated radical reactions. Present investigation forms a first comprehensive report on the nutraceutical property of a seafood P. malabarica as a natural source of antioxidants.
 
Date 2013-07-10T07:09:01Z
2013-07-10T07:09:01Z
2013
 
Type Journal Article
 
Identifier Turkish Journal of Biochemistry, vol.38(2); 2013; 138-144
http://drs.nio.org/drs/handle/2264/4329
 
Language en
 
Rights 2013 ? TurkJBiochem.com - Open Access
 
Publisher Turkish Biochemical Society