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Bis(indolyl)methane alkaloids: Isolation, bioactivity, and syntheses

DRS at CSIR-National Institute of Oceanography

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Title Bis(indolyl)methane alkaloids: Isolation, bioactivity, and syntheses
 
Creator Praveen, P.
Parameswaran, P.S.
Majik, M.S.
 
Subject CHEMISTRY AND BIOGEOCHEMISTRY
MICROBIOLOGY
AQUATIC RESOURCES
 
Description Bis(indolyl)methane (BIM) alkaloids are an important group of bioactive natural products predominantly found in marine organisms. Thus, compounds like arsindoline A and B, vibrindole A, arundine, and trisindoline are found in marine bacteria, while the related compound, streptindole is obtained from Streptococcus faecium IB 37, found in human feces. In recent years, these molecules, which display a wide range of biological properties (antibacterial, antiviral, anti-oxidant, neurotoxic activity etc.), have attracted the attention of several synthetic and natural product chemists. This review lists selected bis(indolyl) methane analogues reported from different natural sources to date, together with their biological properties and synthesis
 
Date 2015-09-08T10:12:23Z
2015-09-08T10:12:23Z
2015
 
Type Journal Article
 
Identifier Synthesis, vol.47; 2015; 1827-1837
no
http://drs.nio.org/drs/handle/2264/4791
 
Language en
 
Relation Synthesis_47_1827.jpg
 
Rights An edited version of this paper was published by © 2012 Georg Thieme Verlag Stuttgart. Published version available at http://dx.doi.org/10.1055/s-0034-1380415
 
Publisher Georg Thieme Verlag Stuttgart