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Large-scale bioprospecting of cyanobacteria, micro- and macroalgae from the Aegean Sea

DRS at CSIR-National Institute of Oceanography

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Title Large-scale bioprospecting of cyanobacteria, micro- and macroalgae from the Aegean Sea
 
Creator Montalvao, S.
Demirel, Z.
PrabhaDevi
Lombardi, V.
Hongisto, V.
Perala, M.
Hattara, J.
Imamoglu, E.
Tilvi, S.
Turan, G.
Dalay, M.C.
Tammela, P.
 
Subject MICROBIOLOGY::General
AQUATIC ECOLOGY, PRODUCTIVITY::Biological productivity
BOTANY::General
BOTANY::Physiology, biochemistry, biophysics
MICROBIOLOGY::Physiology, biochemistry, biophysics
AQUATIC RESOURCES::Natural products
 
Description Marine organisms constitute approximately one-half of the total global biodiversity, being rich reservoirs of structurally diverse biofunctional components. The potential of cyanobacteria, micro- and macroalgae as sources of antimicrobial, antitumoral, anti-inflammatory, and anticoagulant compounds has been reported extensively. Nonetheless, biological activities of marine fauna and flora of the Aegean Sea have remained poorly studied when in comparison to other areas of the Mediterranean Sea. In this study, we screened the antimicrobial, antifouling, anti-inflammatory and anticancer potential of in total 98 specimens collected from the Aegean Sea. Ethanol extract of diatom Amphora cf capitellata showed the most promising antimicrobial results against Candida albicans while the extract of diatom Nitzschia communis showed effective results against Gram-positive bacterium, S. aureus. Extracts from the red alga Laurencia papillosa and from three Cystoseira species exhibited selective antiproliferative activity against cancer cell lines and an extract from the brown alga Dilophus fasciola showed the highest anti-inflammatory activity as measured in primary microglial and astrocyte cell cultures as well as by the reduction of proinflammatory cytokines. In summary, our study demonstrates that the Aegean Sea is a rich source of species that possess interesting potential for developing industrial applications
 
Date 2016-04-11T05:56:21Z
2016-04-11T05:56:21Z
2016
 
Type Journal Article
 
Identifier New Biotechnology, vol.33(3); 2016; 399-406
http://drs.nio.org/drs/handle/2264/4941
 
Language en
 
Rights An edited version of this paper was published by Elsevier. Copyright [2016] Elsevier
 
Publisher Elsevier