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Lipase catalyzed asymmetric synthesis of (R)-melonol

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Title Lipase catalyzed asymmetric synthesis of (R)-melonol
 
Creator Syam, Sujata
Rane, Monica D
Bhat, Sujata V
 
Subject Asymmetric synthesis
Melonol
Lipases
Transesterification
Hydrolysis
 
Description 1308-1310
Synthesis of optically pure 2,6-dimethyl-5-hepten-1-ol (melonol) has been attempted using lipases. Among three different lipases tested, pig pancreatic lipase (PPL) is found to be suitable for transesterification of (±)-melonol to afford (R)-(+)-melonol with an enantiomeric excess of 94%.
 
Date 2008-08-28T11:29:50Z
2008-08-28T11:29:50Z
2008-08
 
Type Article
 
Identifier 0376-4699
http://hdl.handle.net/123456789/1923
 
Language en_US
 
Publisher CSIR
 
Source IJCB Vol.47B(8) [August 2008]