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p-Toluenesulfonic acid catalyzed rapid and efficient protocol for one-pot synthesis of α-amino nitriles
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View Archive Info| Field | Value | |
| Title |
p-Toluenesulfonic acid catalyzed rapid and efficient protocol for one-pot synthesis of α-amino nitriles
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| Creator |
Reddy, Ch Sanjeeva
Raghu, M |
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| Subject |
p-TsOH
α-amino nitriles One-pot three-component condensation Carbonyl compounds Amines Trimethylsilyl cyanide |
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| Description |
1572-1577
A simple, rapid and efficient practical method for one-pot synthesis of α-amino nitriles has been achieved by a three-component condensation of carbonyl compounds, amines and trimethylsilyl cyanide in the presence of p-toluenesulfonic acid (p-TsOH) as a catalyst at ambient temperature. Operational simplicity, economic consideration, high yield, short reaction time and low toxicity are the key features associated with this protocol. |
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| Date |
2008-10-22T07:38:13Z
2008-10-22T07:38:13Z 2008-10 |
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| Type |
Article
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| Identifier |
0376-4699
http://hdl.handle.net/123456789/2263 |
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| Language |
en_US
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| Publisher |
CSIR
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| Source |
IJCB Vol.47B(10) [October 2008]
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