Record Details

Characterization and nuclease activity of mixed ligand Ni(II) complexes

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Characterization and nuclease activity of mixed ligand Ni(II) complexes
 
Creator Babu, M S Surendra
Krishna, P G
Reddy, K Hussain
Philip, G H
 
Description 1661-1665
Mixed ligand complexes having molecular formulae Ni(L)₂ (L')₂ [where LH = salicylaldoxime(SAO) or 2-hydroxy-acetophenone oxime (HAO); L'
= pyridine or imidazole] have been synthesized and characterized by elemental analysis, molar conductivity, magnetic susceptibility, UV-vis and IR spectra. The magnetic moment and UV data suggest square planar geometry for parent complexes and octahedral geometry for mixed ligand complexes. Electrochemical studies have been carried out by cyclic voltammetry. The active signals are assignable to the Niˡˡ′ˡ redox couple. Binding of metal complexes with calf thymus DNA is revealed by absorption spectrophotometry. The cleavage activity of complexes has been carried out on a double stranded pBR 322 circular plasmid DNA by using gel electrophoresis in the presence and in the absence of oxidant (H₂O₂).
 
Date 2008-12-05T05:31:23Z
2008-12-05T05:31:23Z
2008-11
 
Type Article
 
Identifier 0376-4710
http://hdl.handle.net/123456789/2468
 
Language en_US
 
Relation Int. Cl. ⁸ : C07F15/04
 
Publisher CSIR
 
Source IJCA Vol.47A(11) [November 2008]