Record Details

Mechanistic study of oxidation of sulfacetamide by diperiodatocuprate(III) in aqueous alkaline medium

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Mechanistic study of oxidation of sulfacetamide by diperiodatocuprate(III) in aqueous alkaline medium
 
Creator Naik, P N
Kulkarni, S D
Chimatadar, S A
Nandibewoor, S T
 
Description 1666-1670
The oxidation of sulfacetamide, a sulfonamide drug, by alkaline diperiodatocuprate(III) has been studied at 298 K and at constant ionic strength. The reaction is first order in diperiodatocuprate(III) and has less than unit order in sulfacetamide concentration. The rate constants increase with increase in alkali concentration and decrease with increase in periodate concentration. A mechanism has been proposed wherein monoperiodatocuprate(III) is the active species. The reaction constants involved in the different steps of the mechanism and the activation parameters for the slow step have been computed.
 
Date 2008-12-05T05:33:03Z
2008-12-05T05:33:03Z
2008-11
 
Type Article
 
Identifier 0376-4710
http://hdl.handle.net/123456789/2472
 
Language en_US
 
Relation Int. Cl. ⁸ : C07B33/00
 
Publisher CSIR
 
Source IJCA Vol.47A(11) [November 2008]