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Synthesis of quinazolinone analogues using sodium perborate as catalyst
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View Archive Info| Field | Value | |
| Title |
Synthesis of quinazolinone analogues using sodium perborate as catalyst
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| Creator |
Kidwai, Mazaahir
Priya |
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| Subject |
Sodium perborate
Quinazolin-4-ones 2-aminobenzonitrile Microwave irradiation (MWI) Solvent-system |
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| Description |
1876-1881
An environmentally benign approach for the synthesis of 2-aryl-3H-quinazolin-4-ones employing sodium perborate (SPB) as catalyst is described. SPB in water and acetone system is proved as selective catalyst of hydration for cyanides. The rate enhancement and high yield is attributed to the coupling of suitable catalyst with the solvent system. The key step is the microwave prompted reaction sequence combining 2-aminobenzonitrile and aromatic/heteroaromatic aldehydes providing efficient access to intermediate for the synthesis of this important class of nitrogen fused heterocycle. |
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| Date |
2009-01-13T05:46:16Z
2009-01-13T05:46:16Z 2008-12 |
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| Type |
Article
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| Identifier |
0376-4699
http://hdl.handle.net/123456789/2751 |
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| Language |
en_US
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| Publisher |
CSIR
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| Source |
IJCB Vol.47B(12) [December 2008]
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