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Quantitative Structure Activity Relationship study for the nematicidal activity of O,O-diaryl O-n-propyl phosphorothionates

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Title Quantitative Structure Activity Relationship study for the nematicidal activity of O,O-diaryl O-n-propyl phosphorothionates
 
Creator Gupta, R L
 
Subject QSAR
Phosphorothionates
Organophosprous compounds
Nematicidal activity
Meloidogyne incognita
Rotylenchulus reniformis
 
Description 1882-1885
The relationship between the structure of a series O,O-diaryl O-n-propyl phosphorothionates and their nematicidal activity against Meloidogyne incognita and Rotylenchulus reniformis has been analysed using physicochemical parameters for hydrophobic, electronic and steric properties of the molecules by means of multiple regression analysis. The QSAR study has revealed that the nematicidal activity against both nematodes is dependent on the steric parameter for length of the para substituent [ΣL(p)] and electronic nature [Σσ] of the phenyl ring substituents. Different other parameters i.e. hydrophobicity (Σπ) against M. incognita and bulkiness of para substituent [ΣMR(p)] and length of meta substituent [ΣL(m)] against R. reniformis are also found influencing the respective nematicidal activity.
 
Date 2009-01-13T06:19:18Z
2009-01-13T06:19:18Z
2008-12
 
Type Article
 
Identifier 0376-4699
http://hdl.handle.net/123456789/2752
 
Language en_US
 
Publisher CSIR
 
Source IJCB Vol.47B(12) [December 2008]