Synthesis of N-(substituted benzyl)-2-(3′,5′-dimethyl-4′-hydroxyphenyl) acetamides
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Title |
Synthesis of N-(substituted benzyl)-2-(3′,5′-dimethyl-4′-hydroxyphenyl) acetamides
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Creator |
Raju, B China
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Subject |
Acetamides
4-benzyloxy-3,5-dimethylphenylacetate Substituted benzyl amines Tetrahydroisoquinolines |
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Description |
1903-1905
4-Benzyloxy-3,5-dimethylphenylacetate 1 reacts with substituted benzyl amines 2a-e affords N-substituted benzyl-2-(4′-benzyloxy-3′,5′-dimethylphenyl) acetamides 3a-e, which on debenzylation give N-substituted benzyl-2-(3′,5′-dimethyl-4′-hydroxy phenyl) acetamides 4a-e in very good yields which are important intermediates for the synthesis of 1,2,3,4-tetrahydroisoquinolines. |
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Date |
2009-01-13T05:27:54Z
2009-01-13T05:27:54Z 2008-12 |
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Type |
Article
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Identifier |
0376-4699
http://hdl.handle.net/123456789/2748 |
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Language |
en_US
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Publisher |
CSIR
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Source |
IJCB Vol.47B(12) [December 2008]
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