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Conformational studies of nonapeptide using NMR
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View Archive Info| Field | Value | |
| Title |
Conformational studies of nonapeptide using NMR
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| Creator |
Tripathi, Jalaj
Desai, Prashant Srivastava, Sudha Cuthino, Evans |
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| Subject |
NMR data
Nona peptide Melanoma Epitope ϒ bend Non-ideal β-turn |
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| Description |
103-109
The present study describes the study of conformation of nonapeptide Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val (YMDGTMSQV), capable of being recognized by melanoma specific T-cells, corresponds to residue 369 to 377 of tyrosenase gene. Secondary structures have been obtained by ¹H NMR and molecular dynamic simulation using CSI values, 2D COSY, NOESY and ROESY, at 500 and 600 MHz in solvent DMSO-d₆. On this basis, nonapeptide shows a ϒ bend and non-ideal type 1 β-turn. |
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| Date |
2009-01-30T11:22:47Z
2009-01-30T11:22:47Z 2009-01 |
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| Type |
Article
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| Identifier |
0376-4699
http://hdl.handle.net/123456789/2931 |
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| Language |
en_US
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| Publisher |
CSIR
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| Source |
IJCB Vol.48B(1) [January 2009]
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