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Synthesis and antimicrobial screening of 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one

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Title Synthesis and antimicrobial screening of 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one
 
Creator Mulwad, V V
Hegde, A S
 
Subject Bromodeoxybenzoin
Dioxane
Furobenzopyran
Herbicidal
Antimicrobial activity
 
Description 128-133
3-Acetyl-4-hydroxy-2H[1]benzopyran-2-one 2a-d has been treated with bromodeoxybenzoin in NaOH, THF:HMPA
to give 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c] benzopyran-4-one 3a-d. This on treatment with aqueous HCl in presence of dioxane gives 4H-3-methyl-2-phenyl furo[3,2-c] benzopyran-4-one 4a-d through acid catalysed 1,2-elimination. All compounds have been screened for antimicrobial activity. They do not show significant activity.
 
Date 2009-01-30T11:29:43Z
2009-01-30T11:29:43Z
2009-01
 
Type Article
 
Identifier 0376-4699
http://hdl.handle.net/123456789/2936
 
Language en_US
 
Publisher CSIR
 
Source IJCB Vol.48B(1) [January 2009]