Synthesis and antimicrobial screening of 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one
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Title |
Synthesis and antimicrobial screening of 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c]benzopyran-4-one
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Creator |
Mulwad, V V
Hegde, A S |
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Subject |
Bromodeoxybenzoin
Dioxane Furobenzopyran Herbicidal Antimicrobial activity |
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Description |
128-133
3-Acetyl-4-hydroxy-2H[1]benzopyran-2-one 2a-d has been treated with bromodeoxybenzoin in NaOH, THF:HMPA to give 4H-2-benzoyl-3-hydroxy-3-methyl-2-phenyl 2,3-dihydro-furo[3,2-c] benzopyran-4-one 3a-d. This on treatment with aqueous HCl in presence of dioxane gives 4H-3-methyl-2-phenyl furo[3,2-c] benzopyran-4-one 4a-d through acid catalysed 1,2-elimination. All compounds have been screened for antimicrobial activity. They do not show significant activity. |
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Date |
2009-01-30T11:29:43Z
2009-01-30T11:29:43Z 2009-01 |
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Type |
Article
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Identifier |
0376-4699
http://hdl.handle.net/123456789/2936 |
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Language |
en_US
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Publisher |
CSIR
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Source |
IJCB Vol.48B(1) [January 2009]
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