ICAR Research Data Repository for Knowledge Management
Tungstate-catalyzed oxidation of triptans with hydrogen peroxide: A novel method for the synthesis of N,N- dimethyltryptamine N-oxides
NOPR - NISCAIR Online Periodicals Repository
View Archive Info| Field | Value | |
| Title |
Tungstate-catalyzed oxidation of triptans with hydrogen peroxide: A novel method for the synthesis of N,N- dimethyltryptamine N-oxides
|
|
| Creator |
Ray, Purna Chandra
Mittapelli, Vasantha Chauhan, Yogendra Kumar Konudula, Babu Rao Tyagi, Om Dutt |
|
| Subject |
Sodium tungstate
Sumatriptan N-oxide Rizatriptan N-oxide Zolmitriptan N-oxide Almotriptan-N-oxide |
|
| Description |
134-136
A straight forward oxidation method of triptans have been described for the synthesis of N,N-dimethyl-2-[5-[substituted-1H-indole-3-yl]ethanamine-N-oxides using sodium tungstate and 30% aqueous hydrogen peroxide solution in the presence of methanesulphonic acid. The significance of the process is its simplicity and efficiency in isolating the triptan N-oxide derivatives as free base and as malate salt. |
|
| Date |
2009-01-30T11:30:04Z
2009-01-30T11:30:04Z 2009-01 |
|
| Type |
Article
|
|
| Identifier |
0376-4699
http://hdl.handle.net/123456789/2937 |
|
| Language |
en_US
|
|
| Publisher |
CSIR
|
|
| Source |
IJCB Vol.48B(1) [January 2009]
|
|