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Influence of ω-6/ω-3 rich dietary oils on lipid profile and antioxidant enzymes in normal and stressed rats

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Title Influence of ω-6/ω-3 rich dietary oils on lipid profile and antioxidant enzymes in normal and stressed rats
 
Creator Benson, M K
Devi, Kshama
 
Subject Atherogenic index
Lipid peroxidation
Mustard oil
PUFA
Sunflower oil
 
Description 98-103
To evaluate the influence of ω-6/ ω-3 poly unsaturated fatty acid (PUFA) containing oils on lipid profile and endogenous antioxidant enzymes in normal and stressed (immobilization) rats, 28 day old male Wistar rats were fed for
45 days with fat enriched special diet (10% fat) prepared with sunflower oil (SO) — ω-6 rich, mustard oil (MO) — ω-3 rich and groundnut oil — control respectively. SO treated normal rats have significantly reduced total cholesterol, high density lipoprotein – cholesterol (HDL-C) and catalase thereby significantly increased the atherogenic index (AI) and lipid peroxidation (LPO). However, treatment with MO increased superoxide dismutase; decreased LPO significantly. Under stress conditions AI and LPO were significantly high with SO and significantly less with MO. In addition, SO decreased HDL-C whereas MO decreased non-HDL-C significantly. Results suggest a protective role against AI and LPO in normal and stress conditions in MO. The quantity of ω-3 fatty acids in dietary oil may play a crucial role in the body against atherogenicity. The findings signify that not just PUFA, but type of PUFA present in dietary oil used is important.
 
Date 2009-02-11T07:11:44Z
2009-02-11T07:11:44Z
2009-01
 
Type Article
 
Identifier 0019-5189
http://hdl.handle.net/123456789/3067
 
Language en_US
 
Publisher CSIR
 
Source IJEB Vol.47(2) [February 2009]