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A convenient one-pot synthesis of series of 3-(2,6-diphenyl-4- pyridyl)hydroquinolin-2-one under microwave irradiation and their antimicrobial activities

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Title A convenient one-pot synthesis of series of 3-(2,6-diphenyl-4- pyridyl)hydroquinolin-2-one under microwave irradiation and their antimicrobial activities
 
Creator Ladani, Niraj K
Patel, Manish P
Patel, Ranjan G
 
Subject Microwave irradiation
2-chloro-3-formyl quinoline
Acetophenone
N-phenacylpyridinium chloride
Krohnke’s reaction condition
 
Description 261-266
A series of 3-(2,6-diphenyl-4-pyridyl)hydroquinolin-2-one 4a-x compounds are synthesized in high yields by one pot cyclocondensation reactions under Krohnke’s reaction conditions using 2-chloro-3-formyl quinoline 1a-d, various acetophenone 2a-f, N-phenacylpyridinium chloride 3 in the mixture of ammonium acetate and acetic acid by microwave irradiation. All the compounds have been characterized by elemental analysis, FT- IR, ¹H and ¹³C NMR, and mass spectral analysis. These compounds have been screened for their antimicrobial activities.
 
Date 2009-03-20T08:34:58Z
2009-03-20T08:34:58Z
2009-02
 
Type Article
 
Identifier 0376-4699
http://hdl.handle.net/123456789/3426
 
Language en_US
 
Publisher CSIR
 
Source IJCB Vol.48B(2) [February 2009]