Record Details

A new fragmentation rearrangement of the N-terminal protected

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title A new fragmentation rearrangement of the N-terminal protected
 
Creator Zhu, Zhen-Tai
Li, Yan-Mei
Guo, Yan-Ting
Sun, Ming
Zhao, Yu-Fen
 
Subject Terminal-protected amino acids
ESI-MS/MS
Electronic migration
Rearrangement
 
Description 372-376
A novel fragmentation rearrangement reaction with a carboxyl oxygen negative charge migration was observed in the N-terminal protected amino acids including Fmoc-protected phosphoserine, phosphothroenine, and phosphotyrosine and their analogues using the electrospray ionization tandem mass spectrometry (ESI-MS/MS). The possible mechanism of a five-membered ring transition state was proposed and supported by the further experiments. It was found that the tendency of the rearrangement was determined by the blocking status of its C-terminal and the reaction was proved to be independent of the N-terminal and side-chain protecting groups of the amino acids.
 
Date 2009-03-20T08:14:58Z
2009-03-20T08:14:58Z
2006
 
Type Article
 
Identifier 0301-1208
http://hdl.handle.net/123456789/3416
 
Language en_US
 
Publisher CSIR
 
Source IJBB Vol.43(6) [December 2006]