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Enantiospecific total synthesis of ent-10,11-thapsan-10-ol
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View Archive Info| Field | Value | |
| Title |
Enantiospecific total synthesis of ent-10,11-thapsan-10-ol
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| Creator |
Srikrishna, A
Anebouselvy, K |
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| Subject |
Enantiospecific
Thapsia garganica thapsane Thapsia villosa |
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| Description |
413-422
First enantiospecific total synthesis of optical antipode of the sesquiterpene 10,11-epoxythapsan-10-ol has been described. (R)-Carvone has been employed as the chiral starting material and a combination of intramolecular alkylation and Criegee fragmentation are employed for intramolecular stereospecific transfer of the chirality. An intramolecular diazoketone cyclopropanation and regioselective cyclopropane ring cleavage reactions have been employed for the creation of the three requisite contiguous quaternary carbon atoms. |
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| Date |
2009-03-25T04:01:30Z
2009-03-25T04:01:30Z 2009 |
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| Type |
Article
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| Identifier |
0376-4699
http://hdl.handle.net/123456789/3464 |
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| Language |
en_US
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| Publisher |
CSIR
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| Source |
IJC-B Vol.48B(03) [March 2009]
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