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Antibacterial activity of crude methanolic ex-tract and its fractions of aerial parts of Anthemis tinctoria

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Title Antibacterial activity of crude methanolic ex-tract and its fractions of aerial parts of Anthemis tinctoria
 
Creator Akgul, Cahit
Saglikoglu, Gulsen
 
Subject Anthemis tinctoria
Antibacterial activity
Pseudo-monas aeruginosa
Staphylococcus aureus
MIC
MBC
 
Description 395-397
The antibacterial activity of the methanolic extract and its frac-tions of aerial parts of Anthemis tinctoria (Asteraceae) was inves-tigated against representative gram-positive Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 29212) and gram-negative strains Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). The activity was con-centrated mainly in the dichloromethane (DCM) and hexane
fractions of crude methanolic extract. The 5 mg of DCM extract per disk produced 15-16 mm of inhibition zone against S. aureus and P. aeruginosa, however, no activity was found against
E. faecalis and E. coli. The hexane fraction showed activity against S. aureus, P. aeruginosa and E. faecalis. As DCM fraction showed the highest antibacterial activity in the disk diffusion
assay, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of only this fraction was determined against S. aureus and P. aeruginosa. These values were found to be in the range of 1.25 to 10 mg/ml.
 
Date 2009-03-30T09:21:50Z
2009-03-30T09:21:50Z
2005-12
 
Type Article
 
Identifier 0301-1208
http://hdl.handle.net/123456789/3545
 
Language en_US
 
Relation A61P31/04
 
Publisher CSIR
 
Source IJBB Vol. 42(6) [December 2005]