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Combined effect of alcohol and cigarette smoke on lipid peroxidation and antioxidant status in rats

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Title Combined effect of alcohol and cigarette smoke on lipid peroxidation and antioxidant status in rats
 
Creator Bindu, M P
Annamalai, P T
 
Subject Alcohol
Cigarette smoke
Lipid peroxidation
Antioxidant status
 
Description 40-44
The effect of long-term administration of alcohol and cigarette smoke independently and both in combination on lipid peroxidation and antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione-S-transferase (GST) was studied in liver, kidney, heart and lungs of albino rats. The levels of peroxidation products viz., malondialdehyde, hydroperoxides and conjugated dienes were increased in all the tissues of alcohol administered and smoke-exposed rats. Activities of SOD and CAT were decreased in alcohol-treated and alcohol and smoke combination groups, but increased in smoke-exposed group. Activities of GPx and GST have shown an increase, while concentration of reduced glutathione was found decreased in all the three groups.
 
Date 2009-03-31T06:07:53Z
2009-03-31T06:07:53Z
2004-02
 
Type Article
 
Identifier 0301-1208
http://hdl.handle.net/123456789/3628
 
Language en_US
 
Publisher CSIR
 
Source IJBB Vol. 41(1) [February 2004]