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Effect of aspartame on circadian oscillations of calcium and inorganic phosphorus in rats

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Title Effect of aspartame on circadian oscillations of calcium and inorganic phosphorus in rats
 
Creator Rajasekar, P
Manivasagam, T
 
Subject Aspartame
circadian rhythm
calcium
inorganic phosphorus.
 
Description 188-190
The effect of aspartame on circadian rhythms of calcium and inorganic phosphorus levels was studied in rats. Acrophase delays in calcium rhythms and advances in inorganic phosphorus rhythms and alteration in mesor values in both rhythms were observed in aspartame-treated rats. However, no change in amplitude values was observed. Oral administration of aspartame leads to increased levels of aspartate in the brain, which could alter the characteristics of calcium and inorganic phosphorus rhythms, possibly by modulating transmission in several areas/nuclei in brain, including retinohypothalamic tract (RHT) and suprachiasmatic nuclei (SCN).
 
Date 2009-04-02T06:29:38Z
2009-04-02T06:29:38Z
2004-08
 
Type Article
 
Identifier 0301-1208
http://hdl.handle.net/123456789/3706
 
Language en_US
 
Publisher CSIR
 
Source IJBB Vol.41(4) [August 2004]