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Activating and inhibitory receptors and their role in Natural Killer cell function

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Title Activating and inhibitory receptors and their role in Natural Killer cell function
 
Creator Srivastava, Raghvendra M
Savithri, B
Khar, Ashok
 
Subject NK cells
receptors
ligands
function
inhibition
activation
cytotoxicity
 
Description 291-299
Last decade has seen a significant advancement in our understanding of the Natural Killer (NK) cell biology and function. Several receptors present on NK cells have been identified, which are involved in either their activation or inhibition. Similarly, a large number of interacting ligands have been identified on the target cells that upon interaction transmit either activating or inhibitory signals. This review is oriented towards understanding the role of these receptors on the NK cells, which are considered as the first line of defense.
 
Date 2009-04-13T10:04:17Z
2009-04-13T10:04:17Z
2003-10
 
Type Article
 
Identifier 0301-1208
http://hdl.handle.net/123456789/3804
 
Language en_US
 
Publisher CSIR
 
Source IJBB Vol.40(5) [October 2003]