Record Details

Synthesis of some new 2-(4-alkylthiophenoxy)-4-substituted-1, 3-thiazoles as possible anti-inflammatory and antimicrobial agents

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Synthesis of some new 2-(4-alkylthiophenoxy)-4-substituted-1, 3-thiazoles as possible anti-inflammatory and antimicrobial agents
 
Creator T, Karabasanagouda
Adhikari, Airody Vasudeva
Dhanwad, Ramgopal
Parameshwarappa, G
 
Subject 2-{[4-(Alkylthio)phenoxy]methyl}-4-aryl-1
3-thia-zoles
4-(substitutedmethyl)-2-{[4-(alkylthio)phenoxy]meth-yl}- 1
3 thiazoles
anti-inflammatory activity
antibacterial
antifungal screening
 
Description 144-152
A series of new 2-{[4-(alkylthio)phenoxy]methyl}-4-substi¬tuted-1,3-thiazoles 4a-q, 6a-j have been synthesized from ethyl [4-(alkylthio)phenoxy]acetates 1a,b through multi-step reaction sequence. The structures of new compounds have been esta¬blished on the basis of their elemental analysis and IR, 1H and 13C NMR and mass spectral data. Selected title compounds have been evaluated for anti-inflammatory activity and in vitro antibacterial testing against two pathogenic strains and antifungal screening against two fungi.
 
Date 2009-04-15T08:54:41Z
2009-04-15T08:54:41Z
2008-01
 
Type Article
 
Identifier 0376-4699
http://hdl.handle.net/123456789/3846
 
Language en_US
 
Publisher CSIR
 
Source IJC-B Vol.47B(01) [January 2008]