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Synthesis of an amino moiety in trovafloxacin by using an in-expensive amidine base, <i style="">N,N</i>-diethylacetamidine

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Title Synthesis of an amino moiety in trovafloxacin by using an in-expensive amidine base, N,N-diethylacetamidine
 
Creator Madhusudhan, G
Balraju, V
Rajesh, T
Narayana, B Venkata
Reddy, R Naveen
 
Subject N,N-Diethylacetamidine
bicyclic hetero compounds
NaBH4/I2-THF
trovafloxacin
antibacterial agent
 
Description 569-573
The simple and in-expensive amidine base, N,N-diethylacetamidine, has been prepared and utilized in the construction of bicyclic hetero compound, 4 and employed for further reduction of amidic carbonyl groups of 4 by using NaBH4/I2-THF condition which is an efficient and commercially viable method to prepare 5 towards the synthesis of amino moiety 1, in Trovafloxacin 2 an antibacterial agent.
 
Date 2009-04-17T04:09:32Z
2009-04-17T04:09:32Z
2009-04
 
Type Article
 
Identifier 0376-4699
http://hdl.handle.net/123456789/3869
 
Language en_US
 
Publisher CSIR
 
Source IJC-B Vol.48B(04) [April 2009]