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Antifouling sesquiterpene from the Indian soft coral, <i style="">Sinularia kavarattiensis</i> Alderslade and Prita

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Title Antifouling sesquiterpene from the Indian soft coral, Sinularia kavarattiensis Alderslade and Prita
 
Creator Mol, V P Limna
Raveendran, T V
Parameswaran, P S
Kunnath, R J
Sathyan, N
 
Subject Soft coral
Sinularia kavarattiensis
Sesquiterpene
Furoic acid
Balanus amphitrite
 
Description 270-273
A sesquiterpene, (l'E,5'E)-2-(2',6'-dimethylocta-l',5',7'-trienyl)-4-furoic
acid [1], was isolated for the first time from the soft coral Sinularia kavarattiensis Alderslade
& Prita collected from Gulf of Mannar (Tamil Nadu, India). This compound
exhibited considerable larval settlement inhibition properties against the
cosmopolitan biofouler, Balanus
amphitrite. The observed mean EC50
value of 11.21 µg/ml is well within the biological potency cut off set for
natural product antifoulants (NPA’s). The low EC50 value and
favourable therapeutic ratio (5.16) coupled with its known synthetic routes
enhances the potential of 1 as a
promising NPA.
 
Date 2010-07-29T11:12:11Z
2010-07-29T11:12:11Z
2010-06
 
Type Article
 
Identifier 0975-1033 (Online); 0379-5136 (Print)
http://hdl.handle.net/123456789/10022
 
Language en_US
 
Publisher CSIR
 
Source IJMS Vol.39(2) [June 2010]