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Free radical scavenging and anti-inflammatory potential of a marine brown alga <i style="">Turbinaria ornata </i>(Turner) J.Agardh

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Title Free radical scavenging and anti-inflammatory potential of a marine brown alga Turbinaria ornata (Turner) J.Agardh
 
Creator Ananthi, S
Gayathri, V
Chandronitha, C
Lakshmisundaram, R
Vasanthi, Hannah R
 
Subject Turbinaria ornata
Seaweed
Free radical scavenging
Antioxidant
Inflammation
Anti-inflammatory
 
Description 664-670
In the
present study, in-vitro free radical scavenging potential of aqueous extract of Turbinaira ornata (ATO) was evaluated by 1,
1-diphenyl-2-pricrylhydrazyl (DPPH) inhibition assay, Nitric oxide (NO) radical
scavenging assay, lipid peroxide (LPO) inhibition and ABTS radical scavenging
assay. Further, the
anti-inflammatory effect of ATO was evaluated by carrageenan induced paw edema
in rats and vascular permeability assay in mice. ATO showed maximum DPPH and NO
scavenging activity at 500 and 250 µg/mL respectively. Maximum LPO inhibition
was found to be at 62 µg/mL by ATO. Maximum ABTS scavenging assay was found to
be 95.63% at 1000 µg/mL. On the other hand the in-vivo anti-inflammatory activity of the aqueous extract of T.ornata showed a significant (P
 
Date 2011-11-18T04:28:18Z
2011-11-18T04:28:18Z
2011-10
 
Type Article
 
Identifier 0975-1033 (Online); 0379-5136 (Print)
http://hdl.handle.net/123456789/13078
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJMS Vol.40(5) [October 2011]