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Studies on biochemical and biological properties of turrids venom (<i>Turricula javana</i> <i>and</i> <i>Lophiotoma indica</i>) <b>[RETRACTED ARTICLE]</b>

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Title Studies on biochemical and biological properties of turrids venom (Turricula javana and Lophiotoma indica) [RETRACTED ARTICLE]
 
Creator Arumugam, M
Giji, S
Tamilmozhi, S
Kumar, Sunil
Balasubramanian, T
 
Subject Turrids
Marine toxin
HPLC
HPTLC
Peptides
Pharmacology
Venom
Evolution
 
Description 800-806
Turritoxins were isolated from the venom
ducts of Turrid snails Turricula javana and
Lophiotoma indica collected from
Parangipettai waters, south east coast of India. Venom duct yield 1 g/Kg was
dissected from both the species. Crude venom exhibited protein concentration of
0.138mg/ml and 6mg/ml respectively. Venom containing toxicity was analyzed by
SDS-PAGE and revealed their protein bands with an apparent molecular weight of
25 kDa, 41 kDa and 95 kDa for T. javana and
28 kDa and 66 kDa for L. indica. Many
components with molecular mass ranging 29-97kDa exhibited prominent
caseinolytic and gelatinolytic activities with prominent hemolytic acitivty
upto the dilution of 10-6. The lethal concentration, LC50
was determined in Artemia salina. In
addition, the quantitative status of free amino acids was performed through
HPTLC. Presence of peptides was revealed by using HPLC, which was indicative of
viable biological properties.
 
Date 2013-12-13T12:43:30Z
2013-12-13T12:43:30Z
2013-10
 
Type Article
 
Identifier 0975-1033 (Online); 0379-5136 (Print)
http://hdl.handle.net/123456789/24809
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJMS Vol.42(6) [October 2013]