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Microfouling inhibitors from the Indian gorgonian Subergorgia reticulata (Ellis and Solander, 1786)

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Title Microfouling inhibitors from the Indian gorgonian Subergorgia reticulata (Ellis and Solander, 1786)
 
Creator Mol, V.P. Limna
Abhilash, K.R.
Raveendran, T.V.
Parameswaran, P.S.
 
Subject Biofouling
Microfouling
Antifouling
Subergorgia reticulata
Calamenenes
 
Description 2094-2100
Antifouling
research currently focuses on greener ways of biofouling control in view of the
International Maritime Organisation (IMO)
imposed regulations on toxic biocides. Microfouling, the initial phase of
fouling, is an important target to prevent further macrofouling assemblage. In
this perspective, the antimicrofouling potential of three calamenene
derivatives (2-methoxy calamenene, 1;
2,5-dimethoxy calamenene, 2 and 2-methoxy, 5-acetoxy calamenene, 3 isolated from the Indian gorgonian Subergorgia reticulata was investigated.  These compounds inhibited growth of five
fouling bacterial strains (Bacillus
megaterium, Vibrio furnissii, V. fischeri, V. gazogenes and V.
parahaemolyticus) as well as the two species of diatoms (Amphora coffeaeformis and Navicula transitans). Of these, the highest activity was exhibited by
compound 3 against B. megaterium
(MIC, 12.5µg) and N. transitans (EC50,14µg/ml).
The environmental-compatibility of this compound was evidenced from the
non-toxicity to B. amphitrite nauplii
(IC50 1µg/ml) and Artemia
sp. nauplii (IC50 0.6µg/ml). Analysis of structure-activity
relationship suggested that the acetoxy group present in 3 may be
responsible for the comparatively high antifouling activity
exhibited by this compound.
 
Date 2016-06-30T05:18:46Z
2016-06-30T05:18:46Z
2014-11
 
Type Article
 
Identifier 0975-1033 (Online); 0379-5136 (Print)
http://hdl.handle.net/123456789/34579
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJMS Vol.43(11) [November 2014]