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Anti-hyperglycemic and anti-oxidative effect of aqueous extract of <i style="">Momordica charantia </i>pulp and<i style=""> Trigonella foenum graecum</i> seed in alloxan-induced diabetic rats

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Title Anti-hyperglycemic and anti-oxidative effect of aqueous extract of Momordica charantia pulp and Trigonella foenum graecum seed in alloxan-induced diabetic rats
 
Creator Tripathi, Uma Nath
Chandra, Deepak
 
Subject Alloxan
Diabetic rat
Anti-oxidative effect
Momordica charantia
Trigonella foenum graecum
Anti-hyperglycemic activity
 
Description 227-233
Diabetes is an oxidative stress disorder and oxidative damage to tissues
such as heart, kidney, liver and other
organs may be a contributory factor to several diabetic complications. Momordica charantia (family:
Cucurbitaceae) and Trigonella foenum
graecum (family:
Fabaceae)
are used traditionally in Indian folk medicine to manage diabetes mellitus. In
the present study, the anti-hyperglycemic and anti-oxidative potential of
aqueous extracts of M. charantia pulp
and seed powder of T. foenum graecum
were assessed in alloxan (150 mg/kg body weight) induced diabetic rats. Alloxan
treatment to the rats could induce diabetes as the fasting blood glucose (FBG)
levels were >280 mg/dl. Treatment of diabetic rats for
30 days with M. charantia and T. foenum graecum could significantly (p
 
Date 2010-08-23T06:30:58Z
2010-08-23T06:30:58Z
2010-08
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/10122
 
Language en_US
 
Publisher CSIR
 
Source IJBB Vol.47(4) [August 2010]