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Evaluation of antihyperlipidemic activity of ethanolic extract of <i style="">Cassia auriculata</i> flowers

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Title Evaluation of antihyperlipidemic activity of ethanolic extract of Cassia auriculata flowers
 
Creator Vijayaraj, Panneer Selvam
Muthukumar, Kannan
Sabarirajan, Jayaraja
Nachiappan, Vasanthi
 
Subject Atherosclerosis
Hyperlipidemia
Triglycerides
Cholesterol
Cassia auriculata
Antihyperlipidemic activity
 
Description 54-58
Hyperlipidemia is
a major risk factor for development of coronary artery disease. Cassia auriculata is traditionally used in India
for medicinal purposes. In this study, effect of
ethanolic extract of Cassia auriculata flowers
(Et-CAF) was investigated in Triton WR1339-induced hyperlipidemic
rats. Treatment with the Et-CAF (450 mg/kg b.wt) significantly reduced the total cholesterol (TC),
triglycerides (TG) and low-density lipoprotein-cholesterol (LDL) levels and
significantly increased the high-density lipoprotein (HDL) level associated
with reduction of atherogenic index in hyperlipidemic rats. However, there was
no change in the serum lipid profile of normal rats treated with
Et-CAF
alone. The results suggest that Et-CAF has a beneficial effect in treating hyperlipidemia
and may serve as a potential drug for prevention of hyperlipidemic
atherosclerosis.
 
Date 2011-02-25T04:17:41Z
2011-02-25T04:17:41Z
2011-02
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/11106
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.48(1) [February 2011]