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Functional diversity of hnRNP proteins

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Title Functional diversity of hnRNP proteins
 
Creator Singh, O P
 
Description 129-134
The hnRNP proteins bind to pre-mRNA concomitant with
transcription and form ri bonucleoprotein complex essential for post-transcriptional
events. More than 20 different groups of hnRNP proteins are known in humans.
The number seems to be similar in other organisms too. The hnRNP proteins
possess different types of RNA binding domains which directly interact with RNA,
most likely in a sequence specific manner. The functions of hnRNP proteins
range from mRNA packaging and transport, to mRNA splicing and silencing. Further,
indirectly, their role has also been implicated in oogenesis. Hence, hnRNP
proteins play diversified roles both in nucleus and cytoplasm, and regulate the
gene expression at various levels.
 
Date 2012-12-24T18:35:21Z
2012-12-24T18:35:21Z
2001-06
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/15283
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.38(3) [June 2001]