Polyunsaturated fatty acids (PUFA) regulate neurotransmitter contents in rat brain
NOPR - NISCAIR Online Periodicals Repository
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Title |
Polyunsaturated fatty acids (PUFA) regulate neurotransmitter contents in rat brain
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Creator |
Varghese, Sheelu
Shameena, Bake Lakshmy, P S Biju, M P Shankar, Easwar PN Paulose, C S Oommen, V Oommen |
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Description |
327-330
The effects of feeding of 6-propylthiouracil (6-PTU) and polyunsaturated fatty acids (PUFA) independently and in combination and administration (ip) of a single dose of triiodothyronine (T3) (2.5μg/l00g body wt) along with feeding of 6-PTU and PUFA were studied in rat brain. Dopamine (DA), 5-hydroxytryptophan (5-HTP), seroton in (5-HT), 5-hydroxy in dole acetic acid (5-HIAA), norepinephrine (NE) and epinephrine (EPI) contents were assayed in the hypothalamus and cerebral cortex regions. It was found that 6-PTU feeding resulted in decrease in dopamine, 5-HT, 5-HTP and 5-HIAA in both regions. In animals fed with PUFA followed by administration of T3, the DA level was found normal. |
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Date |
2012-12-25T18:36:20Z
2012-12-25T18:36:20Z 2001-10 |
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Type |
Article
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Identifier |
0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/15311 |
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Language |
en_US
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Rights |
CC Attribution-Noncommercial-No Derivative Works 2.5 India
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Publisher |
NISCAIR-CSIR, India
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Source |
IJBB Vol.38(5) [October 2001]
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